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the werewolfs and vampires but mostly the cullens because the cullens drink animal blood so as the werewolfs are animals they hate the cullens for doing wot they do:) hope this helped

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11y ago
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7mo ago

The two groups that are enemies in The Twilight Saga are the vampires, particularly the Cullen family, and the werewolves from the Quileute tribe. Their longstanding enmity stems from their natural rivalry and differing beliefs regarding the treatment of humans.

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Q: What two groups are enemies in The Twilight Saga?
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