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no
No impact on Canada as there was no Canada at the time, other than a small French settlements in the south, little impact on Aborginals other than being the first of many to come Europeans, and the impact in Europe was minor other than showing there were new areas to explore and the possiblity of a NWP which caused more Europeans to trace his routes....except for the last one as no one is sure where he went on that little trip.
the calendar Aztecs
what cantinet did the Europeans
(They had new opportunities) Advancements in medicine during the Industrial Revolution meant more lives were saved.