Check the cylinder.
If it was the only ammunition in the world, I might try. Other wise, NO, NO, NO!!!!!!!!!!!!
No. The ACP has no rim so it cannot be used in a revolver that is not designed to hold the cartridges in a clip. It is also slightly smaller in diameter than the LC (shorter, too, but that shouldn't matter in a revolver). But mostly, if you could get around those differences, the ACP uses smokeless powder and the LC was designed for black powder.
simply put .... no... you need long caliber bullets to fit in the chamber properly Actually, if you have some half moon clips, you can shoot .45acp in a .45LC. You will not be pleased with the results though. Buy some .45 LC ammunition please.
Contact Ruger through their website. IIRC, Ruger has information on their website to check date of manufacture.
If chambered in 45ACP
The colt 1911 fires .45ACP ammunition.
governor.any Smith and Wesson revolver that was made prior to this year(the govenor) that is chambered for a rimless designed cartridge.This includes the .45ACP, the .40S&W,and the 9mm luger cartridges.
$1100 as new and $725 excellent (Standard Catalog of S & W, 2006).
The Model 1911 is a semi-automatic pistol chambered in .45ACP. The Model 1917 is a large frame revolver also chambered in .45ACP but using half-moon or full-moon clips to hold the rounds.
45 cal. Long Colt (.45LC) rounds like those used in a 45 cal. revolver. Many of this type of Derringer also can fire .410 gauge shotgun shells. Do a search for your specific model and get the manufacturers recommendations for ammunition.
The GP100 is a great revolver, but if you're backpacking in Alaska - where you could be subject to encountering bear - you would definitely much rather have the .454 Casull.