commerce can be define as an act of buying and selling goods n services.
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There is no full form of the term 'Commerce'. Commerce means a trade which involves buying and selling of goods which can be inside or outside the country.
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The slave trade was all about commerce where business could make maximum profits from the smallest investments. Labor usually accounts for a very large part of expenditures so free (slave labor) or cheap labor from impoverished societies is always a more lucrative option for commercial exploitation.
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I'm pretty sure that the New England Colonies were themost involved in commerce and trade. Hope this helps.