Halfway between Columbus and Cincinnati
Thornton, IN
Chipley, Florida
Princeton, WV
The halfway point is Rowesville, South Carolina.
Beckley WV or Covington VA are close to halfway and have hotels and food
Cincinnati is he halfway point between Dayton Ohio and Lexington Kentucky. There are 135.61 miles between the two.
It depends, if its by a road or if its straight point to point across land and sea.
Little Rock, Arkansas.
That would be Macon, GA
Ohio is almost 45000 square miles and the halfway point from Cleveland would be different from the halfway point from Cincinnati. Columbus is centrally located. That halfway point is Miami... West Virginia.
If Driving, the halfway point would be in-between Nashville, TN and Memphis, TN. There is no good town indicator. Mile 143 on I-40 might be a good halfway point.