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The driving distance between Columbus, OH and St. Louis, MO is approximately 420 miles. The driving time would be approximately 7 hours if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work, border crossings and rush hour traffic in urban areas.)
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Earn +20 ptsQ: What is the driving distance from st Louis mo to Columbus Ohio?
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