Yes, South of Portland on Interstate Five.
Eugene, OR.
5,240
About 1,382 miles.
175 miles taking I-5 SOUTH.
420 miles down I-5 SOUTH.
220 miles taking I-5 SOUTH.
The Willamette Valley is Oregon's biggest valley. It is 187 miles long stretching from the Columbia River, just north of Portland, Oregon to the headwaters of the Willamette River south of Eugene, Oregon.
It is 1,229 miles according to Google Maps.
You can easily get from Portland to Eugene in a little over two hours. You just take I-5 south.
According to www.mapquest.com: Distance: 1382 miles Driving Time: 20 hours and 37 minutes
A one hour drive south of Portland will take you to Salem, Oregon-- the third largest city in Oregon.