That can't be answered properly because CA and Arizona share a border. You need to specify a location in CA and a location in AZ.
The driving distance from San Diego, CA to University of Arizona, AZ is 410 miles.
The driving distance from Los Angeles, California to Tucson, Arizona is 490 miles.
About 500 miles.
It is 751.56 miles according to MapQuest.
About 220 miles.
660 miles
317 miles
The shortest driving distance is 27 miles.
The shortest driving distance is 59.6 miles.
It is 323.27 miles according to MapQuest.
It is 355.81 miles according to MapQuest.
It is 380.61 miles according to MapQuest.