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The driving distance between Louisville, KY and Biloxi, MS is approximately 675 miles. The driving time would be approximately 11 hours if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work and rush hour traffic in urban areas.)

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14y ago
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13y ago

Google Maps estimates the driving time as 11 hours and 3 minutes.

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15y ago

It is 681.70 miles according to MapQuest.

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Q: How long would it take to drive from Biloxi MS to Louisville KY?
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