Defiance is on the far west border of Ohio near Toledo. It is approximately an 8-hour drive from Defiance Ohio to Buffalo New York. You would take Interstate 80/90 all the way from Defiance to Buffalo.
Cleveland is closer to Buffalo.
60
Buffalo to Cleveland is three hours
329 miles
about three hours
150 miles
It iis 432 miles according to Google Maps.
186 road miles.
They all have waterfronts on Lake Erie.
The address of the Friends Of The Edward Mcotter is: 155 Ohio Street, Buffalo, NY 14203-3049
-Buffalo is not far from Niagara falls -buffalo is in New York
Buffalo, New York is at the other end of the state from New York City.