Paraneoplastic cerebellar degeneration
Paraneoplastic cerebellar degeneration is a paraneoplastic phenomenon associated with lung, ovarian, breast, and other cancers.
It is believed to be due to an autoimmune reaction targeted against components of the central nervous system (specifically Purkinje cells and large brain stem nuclei). It is thought to be caused by an anti-neuronal antibody known as anti-Yo but in lung paraneoplastic cerebellar degeneration, it is thought to be caused by antibody called "anti-Hu".
One of the better characterized paraneoplastic neurologic syndrome is cerebellar ataxia caused by Purkinji cell drop-out in the cerebellum; it is manifested by dysarthria, limb and gait ataxia, and nystagmus. Radiologic imaging reveals cerebellar atrophy. Many antibodies have been associated with this syndrome including anti-Yo, anti-Tr and antibodies to glutamate receptor. A large number of patients with neoplasm-associated cerebellar ataxia who display anti-Yo anti-bodies in the serum typically have a breast or ovarian cancer.
· encephalitis · epilepsy
jaundice
ALS (Lou Gehrig's disease) and African sleeping sickness are diseases. They begin with the letter a.
The Kingdom of Plants starts with p.
Potatoes are veggies. Potato starts with p. :)
Peaceful till the sickness starts!
naupathia - sea sickness
The horse gait that starts with a 'p' is called Piaffe.
A basketball term that starts with P is pass.
Pennsylvania starts with a p \
a word that is similar to hate and starts with a p can be pique!
A party drink that starts with the letter P is punch.