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Q: What protein has cross-bridge heads that pull on the thin fiber?
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What makes a muscle?

A muscle is made of many cylindrical muscle fibers. The many fibers are bound together with connective tissue. Nerves and blood vessels (arteries and veins) run along the connective tissue.In every muscle fiber, there are thick filaments, made of the protein myosin, and thin filaments, made of the protein actin. The filaments overlap to form the sarcomere, a part of the muscle. Myosin has little heads that attach to actin, and pull on it. This is when the sarcomere contracts, and when all of the sarcomeres of a muscle contract, the entire muscle contracts.


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What is a muscle made from?

A muscle is made of many cylindrical muscle fibers. The many fibers are bound together with connective tissue. Nerves and blood vessels (arteries and veins) run along the connective tissue.In every muscle fiber, there are thick filaments, made of the protein myosin, and thin filaments, made of the protein actin. The filaments overlap to form the sarcomere, a part of the muscle. Myosin has little heads that attach to actin, and pull on it. This is when the sarcomere contracts, and when all of the sarcomeres of a muscle contract, the entire muscle contracts.


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What is the crossbridge cycle?

The crossbridge cycle is the cyclical formation of links between actin and myosin. This results in the sliding of thin filaments towards the M line of a sarcomere. The myosin head undergoes conformation changes which allows it to swivel back and forth. In its low energy form, myosin has a low affinity for actin. The ATP prepares myosin for binding with actin by moving it to its high energy form position. When myosin contracts, it has a high affinity for actin.


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