What is the difference between rpc and .NET remoting?

Answer 1

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First off, .Net Remoting is now deprecated in favour of WCF,

WCF is fast and relatively lightweight. The key benefit of WCF though is that it is so configurable. Making pretty much only configuration changes, you can change serilaization format, transport protocol, authentication mechanism, QOS functionality (reliability/security/scalability). Its also extensible enough that if it doesn't provide what you need you can add it yourself. Finally it abstracts application code from communication code.

I'd definately use WCF for new projects. Would I change an existing application from a stable, performant, custom built solution? That depends on the extent of the change, the drawbacks of the existing solution and the potential benefits wcf could bring.