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It stands for a lot such as:SOB, Shortness of Breath (symptom). SOB, School Of Business. SOB, South of the Border. SOB, Summary of Benefits. It also may mean "son of a bitch" if used as an expletive.

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15y ago
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6mo ago

SOB stands for "Shortness of Breath." It is a medical term used to describe difficulty breathing or the sensation of not getting enough air.

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Q: What does SOB stand for?
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