Pythons lay eggs, boas give live birth.
They differ in a lot of other ways as well, including size (pythons are generally bigger), scale pattern and facial features. Pythons sense heat through "pits" along the side of their nose, while boas have heat sensory scales. To name a few.
Chat with our AI personalities
Both pythons and boas are nonvenomous but strong snakes that kill prey by constriction. Both include species that can become very large.