From Wiki:
Shiksa (Yiddish: שיקסע, Polish: Sziksa) or shikse, is a Yiddish and Polish word that has moved into English usage, mostly in North American Jewish culture, where it may be used as a pejorative term for a non-Jewish woman, but is now often used satirically. Among orthodox Jews, the term may be used to describe young Jewish women who fail to follow orthodox religious precepts.