Sydney Harbour was the site of Australia's first European settlement.
The first European on the site that would later become Montreal was Jacques Cartier. if you talk hockey, its mats naslud, swedish in 1985
Captain Arthur Philip was the first governor of the colony of New South Wales, the site of the first European settlement in Australia.
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"Premier state" is the nickname for New South Wales. Its nickname is now "First State" as it was the site of the first official European settlement in Australia.
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The first permanent European settlement in Australia was at Port Jackson, the site of the current city of Sydney. (It was not Botany Bay, as that proved to be unsuitable.)However, there is also some evidence which indicates that the first unofficial European settlements in Australia resulted from survivors of Dutch shipwrecks off the western coast of Australia from the early 1600s through to about the early 1700s.
No, allosteric regulation involves molecules binding to a site other than the active site (allosteric site) to either activate or inhibit enzyme activity. This type of regulation can involve activators or inhibitors that induce conformational changes in the enzyme, affecting its activity.
The first humans to view the Grand Canyon were very likely Native American Indians who were present on the site thousands of years prior to the first known European, García López de Cárdenas, who's expedition located it in 1540.
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