It kinda depends on where in Chinatown you are going (it's a relatively big neighborhood) so I will give you a few different options.
Option 1: Grand Street/Chrystie StreetTake the Manhattan-bound 7 train (the purple line), 1 stop, from 42nd Street-Grand Central to 42nd Street-Bryant Park. Or, just walk 4 blocks west on 42nd Street to 6th Avenue.
Then transfer at 42nd Street-Bryant Park to the Downtown B or D trains (of the B-D-F-M, the orange line) to Grand Street (at Chrystie Street).
Option 2: East BroadwayWalk or take the 7 to 42nd Street-Bryant Park. At Bryant Park, get the Downtown F train to East Broadway (at Rutgers Street).
Option 3: Canal StreetTake the Downtown 6 local train from 42nd Street-Grand Central to Canal Street (at Lafayette Street or Broadway, depending on which entrance/exit you use).
Or, take the Downtown 4 or 5 express trains, 1 stop, from 42nd Street-Grand Central to 14th Street-Union Square. Transfer at Union Square to the Downtown Q express train (of the N-R-Q-W, the yellow line), 1 stop, from 14th Street-Union Square to Canal Street.
Option 4: the BoweryTake the Downtown 4 or 5 express trains, 2 stops, from 42nd Street-Grand Central to Brooklyn Bridge-City Hall. This station is connected to the Chambers Street station on the J-Z (the brown line).
Transfer to the J-Z, and take the Uptown J-Z 2 stops, from Chambers Street to the Bowery (at Kenmare/Delancey Street). Kenmare Street becomes Delancey Street at the Bowery.
It kinda depends on where in Chinatown you are coming from (it's a relatively big neighborhood) so I will give you a few different options.
Option 1: Grand Street/Chrystie StreetTake the Uptown B or D trains (of the B-D-F-M, the orange line) from Grand Street (at Chrystie Street) to 42nd Street-Bryant Park. Transfer at Bryant Park to the Queens-bound 7 train (the purple line), 1 stop, to 42nd Street-Grand Central. Or, just get out at 42nd Street-Bryant Park and walk 3 - 4 blocks east (depending on whether you exit at 6th or 5th Avenue) to Grand Central (at 42nd and Lexington)
Option 2: East BroadwayTake the Uptown F train from East Broadway (at Rutgers Street) to 42nd Street-Bryant Park. Transfer at Bryant Park to the 7 to Grand Central, or, walk.
Option 3: Canal StreetTake the Uptown Q express train (of the N-R-Q-W, the yellow line), 1 stop, from Canal Street (at Lafayette Street or Broadway) to 14th Street-Union Square. Transfer at Union Square to the Uptown 4 or 5 express trains (of the 4-5-6, the dark green line), 1 stop, to 42nd Street-Grand Central.
You can also take the N, R, W or 6trains from Canal Street to 14th Street-Union Square, but these are all local trains so there are more stops.
Option 4: the BoweryGet on the Downtown J-Z (the brown line), at the Bowery (at Kenmare/Delancey Street). Kenmare Street becomes Delancey Street at the Bowery. Take the Downtown J-Z 2 stops, from the Bowery to Chambers Street. This station is connected to the Brooklyn Bridge-City Hall station on the 4-5-6. Transfer to the 4-5-6, and take the Uptown 4 or 5 express trains, 2 stops, to 42nd Street-Grand Central.
take the Shuttle or 7 train from Grand Central to Times Square and transfer to the 1 train uptown to 59th Street/Columbus Circle
Grand central is not that far from the Empire State Building. You could walk it with no problem.
Any Metronorth train that ends at Grand Central puts you on 42nd Street. Grand Central Station is on 42nd Street between Park and Lexington Avenues.
About 15 to 20 minutes.
From Grand Central Station take the 4 or 5 train downtown to the Wall Street stop.
No. Trains to White Plains originate at Grand Central/42nd St. You can walk up to Grand Central (42nd St/Park Avenue), it will take about 20 minutes or take the subway - UPTOWN 1, 2 or 3 train to Times Square-42nd St (one stop), then transfer to the 42nd St Shuttle (S) to Grand Central. Use the staircase at the front of the platform at Grand Central, exit thru the turnstiles, make left then a right. The doors to Grand Central Terminal will be on the left. Fare $2.25
The S shuttle train (color code grey) runs between Grand Central Station (at East 42nd Street) and the Times Square Station (at West 42nd Street).
Take the #60 bus to Grand Central Station, Take the New Haven (Red) Train to New Haven.
Take the S shuttle train (color code grey) east across 42nd Street, from Times Square (West 42nd) to Grand Central Station (East 42nd).At Grand Central Station, transfer to the Uptown 4 train, and take the 4 to 161st Street-Yankee Stadium.
Take the Manhattan-bound 7 train (the purple line), 1 stop, from 42nd Street-Grand Central to 42nd Street-Bryant Park. Transfer at Bryant Park to the M.Or, walk 4 blocks west on 42nd Street from Grand Central (at Lexington Avenue) to 6th Avenue, and get on the subway at 42nd Street-Bryant Park.
The only Number 6 train you may be referring to is the MTA Subway number 6. This train line does not go to NYC Penn Station, but does go to Grand Central Station. The best suggestion is to take the MTA "S" train (for Shuttle) that gives you a very fast trip from Penn Station to Grand Central. There you will find the number 6 train.
Take the Uptown 4 or 5 express trains (of the 4-5-6, the dark green line), 1 stop, from 14th Street-Union Square to 42nd Street-Grand Central Station.