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Will acetaminophen or phenacetin have a higher Rf if you carry out a TLC separation of on a silica gel using a non-polar developing solvent?
Wiki User
∙ 13y ago
Acetaminophen's solubility:
0.1-0.5 g/100 mL at 22 C (Very slightly soluble)
Phenacetin's solubility:
0.076 g/100 mL
Acetaminophen contains Amide & Alcohol groups, thus makes it really polar whereas Phenacetin contains Ether & Amine that are less polar.
Wiki User
∙ 13y ago
Phenacetin will have a higher Rf value than acetaminophen in a TLC separation on silica gel using a non-polar developing solvent. This is because phenacetin is more non-polar than acetaminophen, causing it to move further up the TLC plate and have a higher Rf value.
Wiki User
∙ 13y agophenacetin will have the higher Rf value because it is less polar. Nonpolar molecules travel more quickly through silica gel.
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Are lipids polar or nonpolar?
Lipids are nonpolar molecules, meaning they do not have a charge separation and are hydrophobic (repel water). This property is due to their long hydrocarbon chains that lack significant electronegative atoms, making them insoluble in water.
In which solvents acetaminophen is miscible?
Acetaminophen is most soluble in polar solvents like water, methanol, and ethanol. It is not very soluble in nonpolar solvents like hexane or chloroform.
What is the major force that drives nonpolar substances out of aqueous solution?
The major force that drives nonpolar substances out of aqueous solution is the hydrophobic effect. Nonpolar substances are repelled by water molecules due to water's polar nature. This leads to the aggregation of nonpolar molecules to minimize their contact with water molecules, resulting in their separation from the aqueous solution.
Is a dipole polar or nonpolar?
A dipole is polar because it has a separation of charge, with one end being more positive and the other end more negative. This charge asymmetry gives rise to a net dipole moment, making the molecule polar.
Is ICL4- polar or nonpolar?
nonpolar
Are lipids polar or nonpolar?
Lipids are nonpolar molecules, meaning they do not have a charge separation and are hydrophobic (repel water). This property is due to their long hydrocarbon chains that lack significant electronegative atoms, making them insoluble in water.
What is the polarity of phenacetin?
Phenacetin is a polar compound due to its amide functional group, which contains both polar and nonpolar components. This makes it moderately soluble in polar solvents like water but also allows it to dissolve in nonpolar solvents like organic solvents.
Is Br2 a nonpolar covalent bond?
Yes, Br2 has a nonpolar covalent bond because the two bromine atoms share the electrons equally, resulting in a balanced distribution of charge. This lack of charge separation leads to a nonpolar molecule overall.
Is phenanthrene polar?
No, phenanthrene is nonpolar because it has a symmetrical structure with no separation of charge. This lack of polarity means it is not soluble in water but is soluble in nonpolar solvents.
Is ligroin polar?
No, ligroin is nonpolar because it is a mixture of hydrocarbons with similar electronegativities. This means it does not have a significant separation of charge and does not readily dissolve in polar solvents.
Is ch3ch equals chch2ch3 polar?
No, ch3ch is not polar because it is a nonpolar molecule due to the symmetric arrangement of its carbon and hydrogen atoms. The molecule is nonpolar as the electronegativities of carbon and hydrogen are very similar, resulting in no significant charge separation.
Is paper polar or nonpolar?
Paper is nonpolar because it is mostly composed of cellulose, which is a nonpolar molecule. Nonpolar substances do not have a separation of charge, meaning they do not have a positive and negative end like polar molecules do.
Nonpolar organic molecules are good examples of?
Nonpolar organic molecules are good examples of compounds that do not readily dissolve in water due to their lack of charge separation. Examples include hydrocarbons like fats, oils, and waxes, as well as other nonpolar molecules like benzene and methane.
In which solvents acetaminophen is miscible?
Acetaminophen is most soluble in polar solvents like water, methanol, and ethanol. It is not very soluble in nonpolar solvents like hexane or chloroform.
Which molecules move faster in paper chromatography?
Smaller and less polar molecules generally move faster in paper chromatography because they interact less with the stationary phase (the paper) and can travel more easily through the solvent. Larger and more polar molecules tend to move more slowly as they have stronger interactions with the paper.
What is the best definition of a nonpolar covalent bond?
A nonpolar covalent bond is a type of chemical bond where two atoms share electrons equally because they have similar electronegativities. This results in a balanced distribution of charge and no separation of charge across the bond.
What type of bonds are found in nonpolar molecuels?
Nonpolar molecules typically have nonpolar covalent bonds. These bonds form when atoms share electrons equally, resulting in a balanced distribution of charge and no separation of positive and negative ends in the molecule. Examples of nonpolar molecules with nonpolar covalent bonds include carbon dioxide (CO2) and methane (CH4).
