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Solubility. LAH is not soluble in other solvents which would otherwise be appropriate.

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12y ago
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4w ago

Lah reactions, which involve the addition of an alkyl lithium compound to a carbonyl compound to form a new carbon-carbon bond, are typically conducted in ethers like diethyl ether because ethers can solvate the reactive lithium cation and allow for the reaction to proceed smoothly. Ethers are less acidic and less likely to react with the alkyl lithium reagent compared to other solvents such as alcohols, which can deactivate the alkyl lithium reagent by protonation.

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Q: Why lah reactions can be done in ethers only why not in other solvents?
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