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Frederick Sanger

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15y ago
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5mo ago

Frederick Sanger determined the amino acid sequence of insulin in the 1950s using the technique of protein sequencing. He was awarded the Nobel Prize in Chemistry in 1958 for this achievement.

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Q: Who determined the amino acid sequence of insulin?
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How did scientist find that human genes that make insulin?

Scientists used the amino acid code to find the DNA base sequence,i.e. they worked backwards from mRNA to DNA.They figured out the DNA sequence from the amino acid sequence- APEXthey figured out the dna sequence from the amino acid sequence


Which best describes how scientists the human gene that makes insulin?

They figured out the DNA sequence from the amino acid sequence


Could 2 humans have some differences in their DNA sequence for insulin yet still make the exact same insulin proteins?

Yes, it is possible for two humans to have different DNA sequences for insulin but still produce the exact same insulin proteins. This is because the genetic code is degenerate, meaning that different DNA sequences can code for the same amino acid. As long as the variations in the DNA sequence do not affect the amino acid sequence of the insulin protein, the end product will be the same.


What programs the amino acid sequence of a polypeptide?

There are several computational programs available for predicting the amino acid sequence of a polypeptide. Some commonly used programs include ExPASy Translate tool, EMBOSS Transeq, and the NCBI ORFfinder. These tools take a nucleotide sequence as input and predict the corresponding amino acid sequence by translating the nucleotide sequence based on the genetic code.


How does one protein differ from another protein?

Proteins differ from each other in their amino acid sequence, which is determined by the genetic code. This unique sequence gives each protein its specific structure and function. Differences in amino acid sequence can result in proteins with varying functions, sizes, shapes, and interactions.

Related questions

What determines the amino acid sequence in a protein?

The sequence of amino acids in a protein is determined by the sequence of nucleotides in the mRNA, and this is determined by the sequence of nucleotide bases in the DNA.


How did scientists find the gene that makes insulin?

Scientists used the amino acid code to find the DNA base sequence,i.e. they worked backwards from mRNA to DNA.They figured out the DNA sequence from the amino acid sequence- APEXthey figured out the dna sequence from the amino acid sequence


How did scientist find that human genes that make insulin?

Scientists used the amino acid code to find the DNA base sequence,i.e. they worked backwards from mRNA to DNA.They figured out the DNA sequence from the amino acid sequence- APEXthey figured out the dna sequence from the amino acid sequence


Which best describes how scientists the human gene that makes insulin?

They figured out the DNA sequence from the amino acid sequence


Which best describes how scientists found he human gene that makes insulin?

they worked backwards from mRNA to DNA Ap#x


Which best describes how scientists found the human gene that makes insulin?

They figured out the DNA sequence from the amino acid sequence


What is the amino acid sequence of gcgatatcg?

The amino acid sequence of gcgatatcg cannot be determined directly because it is a DNA sequence. In order to determine the amino acid sequence, the DNA sequence first needs to be transcribed into mRNA and then translated into a protein using the genetic code. Each set of three nucleotides (codon) corresponds to a specific amino acid.


What would be the effects of adding the sequence KDEL to insulin?

KDEL an amino acid sequence which signals that a protein belongs in the endoplasmic reticulum. Attaching it to insulin would cause the insulin to be retained within the endoplasmic reticulum.


How did scientist find the human gene that's makes insulin?

Scientists used the amino acid code to find the DNA base sequence,i.e. they worked backwards from mRNA to DNA.They figured out the DNA sequence from the amino acid sequence- APEXthey figured out the dna sequence from the amino acid sequence


What method did Frederick Sanger use to elucidate the structure of insulin?

analysis of amino acid sequence of small fragments


Could 2 humans have some differences in their DNA sequence for insulin yet still make the exact same insulin proteins?

Yes, it is possible for two humans to have different DNA sequences for insulin but still produce the exact same insulin proteins. This is because the genetic code is degenerate, meaning that different DNA sequences can code for the same amino acid. As long as the variations in the DNA sequence do not affect the amino acid sequence of the insulin protein, the end product will be the same.


What programs the amino acid sequence of a polypeptide?

There are several computational programs available for predicting the amino acid sequence of a polypeptide. Some commonly used programs include ExPASy Translate tool, EMBOSS Transeq, and the NCBI ORFfinder. These tools take a nucleotide sequence as input and predict the corresponding amino acid sequence by translating the nucleotide sequence based on the genetic code.