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What type of mutation in the DNA leads to a single change in the amino acid sequence of the protein?
Wiki User
∙ 8y ago
Yes, it already has by changing the amino acid you have a mutation. That one amino acid counld be in the active site of an enzyme and that one amino acid being changed could result in loss of function or reduction in function of the enzyme. Sickle cell animea is caused by a single such amino acid substiution.
Wiki User
∙ 14y ago
A point mutation is a type of mutation in the DNA that leads to a single change in the amino acid sequence of the protein. This can involve the substitution of one nucleotide for another, resulting in the incorporation of a different amino acid into the protein sequence.
Wiki User
∙ 10y agoNot always. Mutations in condons do not change the amino acid sequence.
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Which genetic change is best described by the following statement A random change in the base sequence of DNA results in an alteration of a polypeptide?
A point mutation is best described by this statement. Point mutations occur when there is a change in a single nucleotide base in the DNA sequence, which can lead to changes in the corresponding amino acid sequence of a polypeptide during protein synthesis.
What is one or two nucleotides that are changed in a certain mutation?
In a point mutation, a change in a single nucleotide can lead to a specific mutation. For example, a substitution mutation occurs when one nucleotide is swapped for another, such as A to T or C to G. This change can result in different amino acids being coded for in the protein sequence.
How a change in the sequence of nucleotides in a strand of DNA might cause a protein to malfunction?
A change in the DNA sequence, such as a point mutation, can result in a different amino acid being incorporated into the protein during translation. This can alter the protein's structure, possibly affecting its function or leading to improper folding. In some cases, the mutation may introduce a premature stop codon, resulting in a truncated and non-functional protein.
How can a point mutation alter the final structure of a protein?
A point mutation can alter the final structure of a protein by changing a single nucleotide in the DNA sequence, leading to a different amino acid being incorporated into the protein sequence during translation. This change can disrupt the folding of the protein, affect its stability, alter its function, or impact its interaction with other molecules. Ultimately, these changes can result in a protein with different structural and functional properties than the original protein.
What does a DNA molecule look like with a mutation?
A DNA molecule with a mutation may have a change in its nucleotide sequence, leading to alterations in the structure of the molecule. This can manifest as a point mutation (single base pair change), insertion or deletion of nucleotides, or rearrangement of segments of DNA. The mutation can disrupt the normal functioning of the gene or protein coded by that segment of DNA.
Can a point mutation be frameshift mutation?
No
Suppose part of an amino acid sequence of a protein changed from tyrosine proline glycine alanine to tyrosine histidine glycine alanine this change was most likely caused by a point mutation called?
This change was most likely caused by a point mutation called a missense mutation. Missense mutations involve the substitution of a single nucleotide in the DNA sequence, leading to a change in one amino acid in the protein sequence. In this case, the substitution of a single nucleotide led to the change from tyrosine to histidine in the protein sequence.
What is the difference between point and non-synonymous mutation?
A point mutation is a change in a single nucleotide in the genetic code, while a non-synonymous mutation is a type of point mutation that causes an amino acid change in the resulting protein. Non-synonymous mutations can affect the function of the protein, while synonymous mutations do not change the amino acid sequence.
Which type of mutation results in the formation of a protein with one incorrect amino acid-?
A point mutation, specifically a missense mutation, is responsible for the formation of a protein with one incorrect amino acid. This type of mutation involves a single nucleotide change in the DNA sequence, leading to the substitution of one amino acid in the protein.
Which genetic change is best described by the following statement A random change in the base sequence of DNA results in an alteration of a polypeptide?
A point mutation is best described by this statement. Point mutations occur when there is a change in a single nucleotide base in the DNA sequence, which can lead to changes in the corresponding amino acid sequence of a polypeptide during protein synthesis.
What is one or two nucleotides that are changed in a certain mutation?
In a point mutation, a change in a single nucleotide can lead to a specific mutation. For example, a substitution mutation occurs when one nucleotide is swapped for another, such as A to T or C to G. This change can result in different amino acids being coded for in the protein sequence.
How a change in the sequence of nucleotides in a strand of DNA might cause a protein to malfunction?
A change in the DNA sequence, such as a point mutation, can result in a different amino acid being incorporated into the protein during translation. This can alter the protein's structure, possibly affecting its function or leading to improper folding. In some cases, the mutation may introduce a premature stop codon, resulting in a truncated and non-functional protein.
Any change or random error in DNA sequence?
A mutation is a change in the DNA sequence that can occur randomly or be induced by external factors. Mutations can range from a single nucleotide change to larger deletions or duplications. These changes can influence characteristics like protein structure and function, potentially leading to genetic disorders or other biological effects.
How can a point mutation alter the final structure of a protein?
A point mutation can alter the final structure of a protein by changing a single nucleotide in the DNA sequence, leading to a different amino acid being incorporated into the protein sequence during translation. This change can disrupt the folding of the protein, affect its stability, alter its function, or impact its interaction with other molecules. Ultimately, these changes can result in a protein with different structural and functional properties than the original protein.
A point mutation involves a change in an?
A point mutation involves a change in a single nucleotide base in a DNA sequence. This can result in a new amino acid being incorporated into a protein during translation, potentially leading to changes in the protein's function.
What does a DNA molecule look like with a mutation?
A DNA molecule with a mutation may have a change in its nucleotide sequence, leading to alterations in the structure of the molecule. This can manifest as a point mutation (single base pair change), insertion or deletion of nucleotides, or rearrangement of segments of DNA. The mutation can disrupt the normal functioning of the gene or protein coded by that segment of DNA.
What does a missense mutation look like?
A missense mutation is a type of genetic mutation where a single nucleotide change results in a codon that encodes a different amino acid in the protein sequence. This can lead to a change in the protein's structure and function, affecting its normal activity. Detecting missense mutations typically involves analyzing the DNA sequence and predicting the potential impact on protein function.
