Ribosomes make Rough ER have a rough appearance. Smooth ER does not have ribosomes, and therefore has a smooth appearance.
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The rough endoplasmic reticulum appears rough due to the presence of ribosomes on its surface, which are responsible for protein synthesis. These ribosomes give the rough ER its bumpy or studded appearance, distinguishing it from the smooth endoplasmic reticulum, which lacks ribosomes and appears smooth.
Presence of ribosomes on the membrane of endoplasmic reticulum makes the surface look bumpy.
ribosomes
The rough endoplasmic reticulum(RER) appear rough when observed under a microscope because the outer region of the RER is studded with ribosomes which form sites for protein synthesis.
In translation, messenger RNA and transfer RNA and ribosomes work together to produce proteins. Ribosomes are very tiny particles that are present in large numbers in all living cells and serve as the site of protein synthesis.
The rough endoplasmic reticulum (ER) has ribosomes attached to its surface, giving it a rough appearance, while the smooth ER lacks ribosomes, making it look smooth. The rough ER is involved in protein synthesis and processing, while the smooth ER is involved in lipid synthesis, detoxification, and calcium storage.