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Polydactyly is caused by a congenital physical anomaly, which is caused by damage to a developing fetus. This may be a result of genetic abnormalities, the uterine environment, errors of morphogenesis, or a chromosomal abnormality.

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14y ago
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4mo ago

Polydactyly in humans can be caused by mutations in specific genes that are involved in limb development, such as the homeobox (HOX) genes. These mutations can result in extra fingers or toes being formed during embryonic development. Polydactyly can also be inherited in a Mendelian fashion, with mutations in genes like GLI3 and SHH that regulate limb patterning.

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Q: What kind of mutations cause polydactyly in humans?
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