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The summation of graded potentials refers to the combined effect of multiple depolarizations or hyperpolarizations occurring simultaneously at different locations on a neuron. These individual changes in membrane potential can be added together to influence the overall excitability and likelihood of the neuron firing an action potential. Summation can be either spatial (when inputs come from different locations) or temporal (when inputs occur at different times).
Action potential
the four phases of temporal summation are : fatigue, incomplete tetanus, treppe & complete tentanus.
Summation occurs, where the two excitatory postsynaptic potentials combine to reach the threshold for firing an action potential. This can be either temporal summation, where two EPSPs from the same presynaptic neuron occur in quick succession, or spatial summation, where EPSPs from different presynaptic neurons arrive simultaneously.
The process of adding the effects of many postsynaptic potentials is called summation. There are two types of summation: temporal summation, where postsynaptic potentials from the same presynaptic neuron add up over a short period of time, and spatial summation, where postsynaptic potentials from multiple presynaptic neurons add up at the same time. Summation ultimately determines whether an action potential will be generated in the postsynaptic neuron.