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Solubility of Fluoroquinolones

According to: http://aac.asm.org/cgi/content/full/44/3/798#T1
the solubility of fluoroquinolones in water is:
moxifloxacin, 2.4 g/100 ml; sparfloxacin, 0.11 g/100ml; trovafloxacin , 0.002 g/100 ml; ciprofloxacin 3.5 g/100 ml; and levofloxacin 2.5 g/100 ml

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15y ago
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AnswerBot

5mo ago

Levofloxacin is generally soluble in water and acidic solutions, but its solubility can vary depending on factors such as temperature and pH. It is important to consult the specific product information or literature to determine the solubility under specific conditions.

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10y ago

You can't. Liquid Ciprofloxacin is a "suspension." You shake the bottle until the product is evenly mixed throughout it, pour out the dose and give it to the person taking it, and when you stick the bottle back in the fridge the medicine will sink to the bottom in a short period of time.

However, cipro itself is noted by at least one supplier as being soluble in water (30 mg/ml), so if you don't need it to be too concentrated, just putting it in water and stirring should work. If that fails, salts are generally more soluble than the "free base" form, so you could try that.

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13y ago

ciprofloxacin HCL is more soluble in water than acetone or propan-2-ol.

however some chemists claim it's best soluble in glycerin. i have not personally tried that out though.

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11y ago

How do you dissolve cipro

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12y ago

soluble

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Q: What is the solubility of levofloxacin?
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