answersLogoWhite

0


Best Answer

Carnitine shuttles play a role in fatty-acid metabolism. They are needed to transport fatty acids from the cytosol to the mitochondrial matrix. This process is necessary as fatty acyl CoA can only be oxidized in the mitochondrial matrix to release energy.

Without the carnitine shuttles, the fatty acyl CoA cannot cannot undergo oxidation. The body's production of acetyl CoA hence decreases as acetyl CoA is one of the products generated by the oxidation of acyl CoA. Glucose production is not stimulated and this leads to hypoglycemia, impairing brain functions and potentially leading to the loss of consciousness.

User Avatar

Wiki User

8y ago
This answer is:
User Avatar
More answers
User Avatar

AnswerBot

1y ago

Carnitine shuttles play a crucial role in cellular energy metabolism. They transport long-chain fatty acids into the mitochondria, where they can be oxidized to generate ATP. This process is important for fueling the energy needs of tissues such as the heart and skeletal muscles.

This answer is:
User Avatar

Add your answer:

Earn +20 pts
Q: What is the physiological significance of carnitine shuttles?
Write your answer...
Submit
Still have questions?
magnify glass
imp
Related questions

How do the carnitine shuttles work?

The carnitine shuttles help transport fatty acyl coA from the cytosol of the cell into the mitochondrial matrix. The acyl group is first transfered to a carnitine and it is catalyzed into fatty acyl-carnitine by carnitine acyltransferease I at the outer mitochondrial membrane. The fatty acyl-carnitine then moves through the intermembrane space of the mitochondria through the transporter carnitine-acylcarnitine translocase. When the acyl group reaches the matrix, it is transferred to mitochondrial CoA, it is catalyzed by carnitine acyltransferase II to reform fatty acyl CoA. The carnitine is regenerated and it moves back to the intermembrane space with the aid of the same transporter.


What has the author Elizabeth Ann Snyder written?

Elizabeth Ann Snyder has written: 'The effect of dietary carnitine on excretion of urinary and milk carnitine in adult and lactating women' -- subject(s): Physiological effect, Carnitine


What is n-acetyl l-carnitine used for?

N-acetyl-L-carnitine is a dietary supplement which breaks down in the body to produce carnitine. L-carnitine (the active isomer of carnitine) is useful in metabolism of fatty acids. Check the animation in the related links below to understand that biochemistry of L-carnitine


Does sweet potato have l carnitine?

They do not. Meats are high in carnitine, dairy is moderate in carnitine, and trace amount can be found in peanuts and avocados.


What is the difference between acetyl l carnitine hydrochloride and acetyl l carnitine?

Acetyl L-carnitine and acetyl L-carnitine hydrochloride are two forms of the same compound. The only difference lies in the type of salt they are combined with. Acetyl L-carnitine hydrochloride is the hydrochloride salt form of acetyl L-carnitine.


What is the difference between acetyl L-carnitine and L-carnitine?

One has acetyl in front of it.


What are the symptoms of carnitine deficiency?

Symptoms of inadequate carnitine can include confusion, heart pain, muscle weakness, and obesity.


Who should not take carnitine supplements?

Women who are pregnant or may become pregnant should not take carnitine supplements.


What vegetarian foods contain L-carnitine?

I believe l-carnitine is an amino acid produced by the body and also made syntheticly


Why carnitine deficiency causes impaired gluconeogenesis?

Carnitine deficiency can impair gluconeogenesis because carnitine is necessary for the transport of fatty acids into the mitochondria for beta-oxidation. Without adequate carnitine, there is a buildup of fatty acids in the cytoplasm, leading to an imbalance of acetyl-CoA, which can inhibit gluconeogenesis. This can result in decreased glucose production and energy production in the liver.


Is l-carnitine and levocarnitine same thing?

Yes, they are. Carnitor and Levocarnitine are two medical brand names of l-carnitine that are prescribed by doctors for the deficiency. L-carnitine can be purchased OTC at many vitamin outlets if desired.


What acid is present in animals?

carnitine