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The most severe form of ALD is called childhood ALD. About 35% of people with ALD have this type. These children usually have normal development in the first few years of life.

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13y ago
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6mo ago

The most severe form of adrenoleukodystrophy is known as cerebral adrenoleukodystrophy (CALD). This form primarily affects the brain and progresses rapidly, leading to severe neurological symptoms such as loss of cognitive function, movement disorders, and ultimately disability or death. Early detection and treatment are critical in managing CALD.

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Q: What is the most severe form of adrenoleukodystrophy?
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The childhood form of the disease is the classical form and is the most severe. Childhood ALD is progressive and usually leads to total disability or death. It affects only boys because the genetic defect is sex-linked.


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