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They are present in all six layers of cortex (except layer 1). Whenever Pyramidal neurons (another type of neurons that are also found in cortical layers) are over-excited, cells of Martinotti will send inhibitory signals to surrounding neurons. Simply, they are involved in "cortical dampening mechanism".
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DevinCells of Martinotti are inhibitory interneurons found in the cerebral cortex. They play a role in regulating neural activity by providing feedback inhibition to pyramidal neurons. Martinotti cells are involved in processing information and fine-tuning the balance of excitation and inhibition within neural circuits.
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