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DNA polymerase III is the main enzyme responsible for replicating DNA during cell division in prokaryotic cells. It synthesizes new DNA strands by adding nucleotides to a pre-existing DNA template. It is highly processive, meaning it can copy long stretches of DNA without falling off the template strand.
The first nucleotide must be attached to a short RNA primer to provide a free 3' hydroxyl group for DNA polymerase to extend from. DNA polymerase starts adding nucleotides to this RNA primer to begin DNA replication.
During DNA replication, DNA polymerase lands at the origin site and begins synthesizing a new DNA strand complimentary to the template strand. It catalyzes the addition of nucleotides to the growing DNA chain in a 5' to 3' direction. This process is essential for the accurate duplication of genetic information.
A primer molecule is required for DNA polymerase to initiate the addition of nucleotides. This primer provides a starting point for DNA polymerase to begin adding nucleotides in the correct sequence. Once the primer is in place, DNA polymerase can add nucleotides complementary to the template strand.
Cells come from pre-existing cells through the process of cell division. Genetic information is passed on as DNA during reproduction, carrying the blueprint for life encoded in genes. Changes in the DNA sequence can result in variations and adaptations in living organisms over time through the process of evolution.