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When a repressor is bound to the operator, it physically blocks the RNA polymerase from binding to the promoter region of the gene, preventing transcription. This mechanism effectively shuts down gene expression by inhibiting the initiation of transcription of that specific gene.

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Q: What happens when a repressor is bound to the operator?
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What turns off transcription by binding to the operator?

A repressor protein turns off transcription by binding to the operator region. By binding to the operator, the repressor prevents the RNA polymerase from binding to the promoter region and initiating transcription. This prevents the expression of the gene or genes downstream of the operator.


What state is the repressor protein in when tryptophan is absent?

When tryptophan is absent, the repressor protein is in an inactive state, allowing transcription of the trp operon to continue. This is because the repressor protein needs tryptophan to bind to it, enabling it to attach to the operator region and block transcription of the operon.


The expression of the tryptophan operon is controlled by?

The expression of the tryptophan operon is controlled by a repressor protein that binds to the operator region in the presence of tryptophan. When tryptophan levels are high, the repressor is active and prevents transcription of the operon. When tryptophan levels are low, the repressor is inactive, allowing transcription to occur.


The lac repressor releases the operator in the presence of glucose?

That statement is inaccurate. The lac repressor releases the operator in the absence of glucose but in the presence of lactose. Glucose acts as a catabolite activator protein (CAP) regulator in the lac operon system.


In E. coli the tryprophan switches off the trp operon by?

binding to the trp repressor, causing a conformational change that allows it to bind to the operator region of the trp operon. This blocks RNA polymerase from transcribing the genes, turning off expression of the trp operon.