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CoachIf anti-B antibodies (from someone who is blood type A or AB) are mixed with group B red cells, agglutination or clumping of red cells will occur due to a reaction between the antibodies and the B antigen on the red cells. This can lead to transfusion reactions if incompatible blood is transfused, causing harm to the recipient.
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Why you can give patients with group A blood with group O?
Group O blood is considered the universal donor because it lacks A and B antigens on the red blood cells, reducing the risk of a transfusion reaction in patients with group A blood who have anti-B antibodies. Group O red blood cells are less likely to be attacked by antibodies in the recipient's blood. However, it is important to consider Rh factor compatibility as well.
Why the antibodies anti A and anti B in blood group O do not destroy cells of blood group A or B destroy?
Antibodies anti A and anti B in blood group O do not destroy cells of blood group A or B because individuals with blood group O do not have A or B antigens on their red blood cells. Therefore, they do not recognize A or B antigens as foreign and do not produce antibodies against them. This prevents the destruction of blood cells of other blood groups.
Why blood group o should not receive blood from other groups?
Blood group O individuals are considered universal donors because their blood cells do not have A or B antigens on their surface. If blood group O receives blood from other groups, there is a risk of a transfusion reaction where the recipient's immune system may attack the donor's blood cells which have A or B antigens. This can lead to serious complications or even death.
Will the B antibody in the plasma donor blood group A agglutinate the A antigen of the AB recipient and Why?
Yes. A person with blood group antibody B can not donate blood to another person with group A because it will agglutinates as they blood group A can only be donated to to a person with blood group A. Even though you donate whole blood, all of it is not given unless you both have the exact blood type. A person with A type (who has B antibodies in their plasma) will only donate their cells. No antibodies will be given. So AB can be given A but without the plasma which has the antibodies.
Which White blood cells that activate plasma cells?
Helper T cells (Th2 cells) play a role in activating plasma cells, which are responsible for producing antibodies. Helper T cells release cytokines that stimulate B cells to differentiate into plasma cells and produce specific antibodies against pathogens.
