They involving in water balancing mainly.Also aid to balance ion concentrations.
Mainly hormones like ADH and Aldestorone and ions like Na+
Addison's disease (also called hypoadrenocorticism) occurs when your dog's adrenal glands (each kidney has one gland) stops producing the hormones (cortisol and aldestorone) necessary to regulate sodium in the blood. Without these hormones, sodium levels decline causing an increase potassium and lower blood pressure. The problem is that the higher levels of potassium stop the heart from beating faster, which it would naturally do, such as when there is a loss of blood pressure. With a lower heart rate and lower blood pressure your dog could go into shock (called Addison's crisis). This could be fatal. Addison's disease is treated with several types of medication that help replace the missing hormones from your dog's body. In addition to the medications that your vet may prescribe, it's a good idea that you consider your dog's diet. You want to make sure that your dog is getting the vitamins and nutrients that he needs. Generally that's going to mean stop feeding grocery store brand dog foods. Better quality dog foods list an identified source of meat (such as Chicken, or Beef) as the first ingredient, and contain no artificial preservatives (BHA, BHT, or Ethoxyquin), or artificial colors or dyes. Make sure you check treats for these preservatives, also. You can read more about how to identify better quality dog foods here: Your veterinarian can probably suggest a diet that would be tolerated by your dog.