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These are tumor cells that arose from a single lymphocyte or plasma cell. The kappa light chain is a piece of the structure of an antibody; monoclonal means "single type". Therefore, these are tumor cells that all produce the same antibody structure, which indicates they are all derived from a single tumor cell that originally made this antibody structure.

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4mo ago

Tumor cells that are monoclonal kappa light chain positive express a specific type of immunoglobulin light chain on their surface. This finding is often seen in certain types of B-cell lymphomas or multiple myeloma, indicating that these tumors are derived from a single clone of B-cells that produce this specific light chain. Detection of monoclonal kappa light chain positivity helps in diagnosis and monitoring of these conditions.

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Q: What are tumor cells monoclonal kappa light chain positive?
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