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Q: What are the three steps of pyruvate oxidation?
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What are the substrates and products of pyruvate oxidation?

The substrate of pyruvate oxidation is pyruvate, a three-carbon molecule derived from glycolysis. The products of pyruvate oxidation are acetyl-CoA, which is a two-carbon molecule, and carbon dioxide. This process occurs in the mitochondria and is a crucial step in the aerobic respiration pathway.


What is the exact location of pyruvate oxidation in the mitochondrion?

Pyruvate oxidation takes place in the mitochondrial matrix. Here, pyruvate is converted into acetyl-CoA by the pyruvate dehydrogenase complex, which is a critical step in aerobic respiration.


Is Co2 released during oxidation of pyruvate to acetyl CoA?

Yes, during the oxidation of pyruvate to acetyl CoA in the mitochondria, CO2 is released through decarboxylation reactions. This process is part of the pyruvate dehydrogenase complex, where pyruvate is converted to acetyl CoA, releasing CO2 as a byproduct.


Where in the cell is pyruvate broken down?

Pyruvate is broken down in the mitochondria of the cell through a process called aerobic respiration. Pyruvate is converted into acetyl-CoA, which then enters the citric acid cycle to produce ATP, the cell's main energy source.


Where is oxidation of pyruvate located?

The oxidation of pyruvate occurs in the mitochondria of eukaryotic cells. This process is part of cellular respiration and generates acetyl CoA, which then enters the citric acid cycle to produce ATP.


What is the purpose of pyruvate oxidation?

The purpose of pyruvate oxidation is to convert pyruvate, a product of glycolysis, into acetyl-CoA in the mitochondria. This process generates NADH and releases CO2 as a byproduct. Acetyl-CoA then enters the citric acid cycle to produce more reducing equivalents for ATP production.


What are the products of pyruvate oxidation?

The products of pyruvate oxidation are Acetyl-CoA, NADH, and carbon dioxide. This process occurs in the mitochondria and is a key step in cellular respiration to generate energy.


How many C atoms are in a molecule of pyruvate?

There are three carbon atoms in a molecule of pyruvate.


Where is pyruvate oxidation in bacteria?

Pyruvate oxidation in bacteria occurs in the cytoplasm of the cell. Pyruvate is converted into acetyl-CoA by the enzyme pyruvate dehydrogenase complex, which then enters the TCA cycle in the bacterial cell's cytoplasm or mitochondria.


Which of the following is not a possible fate of the glucose which is taken into cells?

Oxidation to pyruvate via gluconeogenesis


What process occurs before the Krebs cycle?

The formation of acetyl-CoA


What causes excess pyruvate in blood?

Insulin is a hormone that is needed for kreb cycle to function properly. In metabolism of glucose are three steps: 1. glycolysis in which the glucose is converted to pyruvate 2. kreb's cycle - pyruvate is converted to oxaloacetate by pyruvate carboxylase enzyme. 3. Electron transport chain. In diabetes when there is deficiency of insulin, kreb's cycle won't work properly and thus the end product of glycolysis i.e pyruvate will be in excess in blood. Excess of pyruvate will lead to deficiency of pyruvate carboxylase which will lead to lactic acidosis. Also in case of anaerobic condition, the pyruvate will be converted to lactate.