Pharmaceuticl suspensions are solid dipersion of insoluble or sparingly-soluble drugs, in aqueous or oily vehicles. They are intended for oral administration, topical application or parenteral administration of drugs.
Aerosol suspension of finely divided, or micronized drugs, is also another class of pharmaceutical preparations intended for inhalation.
Suspension of drugs for oral administration is an easy way to administer insoluble, or sparingly soluble, drugs to infants and eldery who have difficulty in administering drugs in tablet or capsule forms. Also for rapid absorption of some insoluble drugs, which are slowly absorbed from tablet dosage form, such as griseofulvin, prepared in suspensions form of the micronized drug.
The insoluble basic drug, or the insoluble salt or compound of a drug, is frequently used rather than using the soluble salt, to retard absorption of the drug. This is used for the preparation of prolonged released dosage forms to avoid frequent administration of the drug.
Sometimes insoluble salts or compounds of the dugs are used to avoid the bitter taste of the soluble form; for example the use of chloramphenicol palmitate in suspension, instead of using the very bitter soluble chloramphenicol.
Some eye drops or ear drops are also prepared in suspension form for drugs which are sparingly soluble, or intenetially using the insoluble form to prolong the time of action of the drug, such as corticosteroid preparations. Samir M. Bayoumi
Prof. of Pharmaceutics
samir.bayoumi@mcphs.edu
Some examples of pharmaceutical suspensions include amoxicillin suspension, ibuprofen suspension, and antacid suspensions. These formulations consist of solid particles suspended in a liquid vehicle, providing a way to administer medications orally in a liquid form.
The effects depend on the pharmaceutical drug.
Ideally, you would want a suspension that doesn't have any effects on its own.
Maybe you mean what are the implications of delivering drugs as a suspension instead of other methods?
A suspension is when you have a solid drug in a liquid delivery, but the solid is not dissolved. Instead, it is floating suspended in the liquid.
The advantage to this is that you are essentially administering a ground up tablet in a convenient liquid oral delivery.
One disadvantage is that the solid that is suspended can settle to the bottom, so it is important to always shake a pharmaceutical suspension before taking it.
Prednisolone suspension
E.g. Oxytetracycline suspension
E.g. Chloramphenicol palmitate suspension
absorption.
E.g. Cholera vaccine
E.g. Barium sulphate for examination of alimentary tract
Some examples of animal cell suspension culture include the growth of Chinese hamster ovary (CHO) cells, mouse myeloma cells, and human embryonic kidney (HEK) cells in suspension in a nutrient-rich medium. These cultures are commonly used in biotechnology and pharmaceutical research for protein production and cell-based assays.
In a pharmaceutical suspension, a suspending agent helps the drug stay in the body of your suspension thereby preventing caking at the bottom. One of the properties of a well-formulated suspension is that it can be easily resuspended by the use of moderate agitation.
Physical stability: A good pharmaceutical suspension should maintain uniform distribution of particles over time, without settling or caking. Rheological properties: The suspension should have appropriate viscosity and flow characteristics for easy administration and accurate dosing. Bioavailability: The suspended drug particles should be readily and consistently available for absorption in the body to ensure therapeutic effectiveness.
A suspension is a heterogeneous mixture where solid particles are suspended in a liquid. Food examples include salad dressings, certain types of sauces, and some beverages where particles do not dissolve but remain suspended in the liquid.
An example of a solution suspension is a mixture of water and sand, where the sand particles remain in suspension and can be seen in the liquid. An example of a colloid is milk, which consists of dispersed fat molecules in water, giving it a cloudy appearance.
Some examples of animal cell suspension culture include the growth of Chinese hamster ovary (CHO) cells, mouse myeloma cells, and human embryonic kidney (HEK) cells in suspension in a nutrient-rich medium. These cultures are commonly used in biotechnology and pharmaceutical research for protein production and cell-based assays.
In a pharmaceutical suspension, a suspending agent helps the drug stay in the body of your suspension thereby preventing caking at the bottom. One of the properties of a well-formulated suspension is that it can be easily resuspended by the use of moderate agitation.
mud
sodium acetate tyihydrate
syrup is a pharmaceutical solution that completely dissolves into its solvent, with the distribution of drugs within the solution being even, a suspension is drug mixture whereby the drug particles do not fully dissolve into the solvent.
There are 2 awesome examples of suspension in the human body. The knees and the spine. The spine will contract slightly and act as suspension when jumping and walking. The knees acts as suspension as well.
Orange juice, pond water, and Italian salad dressing are examples of liquid heterogeneous mixtures.
it means developing area of any dosage form like tablet,capsule,syrup,suspension etc. in this laboratories they get the active ingredients and excepients from different suppliers and develops the new products this is called pharmaceutical manufacturing laboratories................
Physical stability: A good pharmaceutical suspension should maintain uniform distribution of particles over time, without settling or caking. Rheological properties: The suspension should have appropriate viscosity and flow characteristics for easy administration and accurate dosing. Bioavailability: The suspended drug particles should be readily and consistently available for absorption in the body to ensure therapeutic effectiveness.
Pharmaceutical research
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Muddy water, paint, and some medicines like pepto bismal.