Electroporation is a dynamic phenomenon that depends on the local transmembrane voltage at each point on the cell membrane. It is generally accepted that for a given pulse duration and shape, a specific transmembrane voltage threshold exists for the manifestation of the electroporation phenomenon (from 0.5 V to 1 V). This leads to the definition of an electric field magnitude threshold for electroporation (Eth). That is, only the cells within areas where E≧Eth are electroporated. If a second threshold (Eir) is reached or surpassed, electroporation will compromise the viability of the cells, i.e., irreversible electroporation.[2]
Electroporation involves the application of an electric field to create temporary pores in the cell membrane, allowing molecules to enter the cell that would normally be too large or hydrophilic to pass through. The electric field disrupts the lipid bilayer, leading to the formation of aqueous pores which facilitate the movement of molecules across the membrane. This technique is commonly used in molecular Biology and biotechnology to introduce substances like DNA or drugs into cells.
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Selective permeability refers to the property of the plasma membrane to allow certain substances to pass through while restricting others. This enables the cell to maintain an internal environment conducive to its function. The plasma membrane achieves selective permeability through various mechanisms such as protein channels and transporters.
Selective Permeability
Cholesterol is not harmful to the plasma membrane; in fact, it plays a crucial role in maintaining the fluidity and stability of the membrane. Cholesterol helps regulate the permeability of the membrane and enhances its mechanical strength.
Selective permeability is the property that describes the plasma membrane's ability to regulate the movement of molecules into and out of the cell, allowing only certain substances to pass through while restricting others. This selective permeability is achieved through the presence of various proteins and lipid components in the membrane.
Electroporation, or electropermeabilization, is a significant increase in the electrical conductivity and permeability of the cell plasma membrane caused by an externally applied electrical field. It is usually used in molecular biology as a way of introducing some substance into a cell, such as loading it with a molecular probe, a drug that can change the cell's function, or a piece of coding DNA.For more details see the link on the left
who the knows
Selective permeability refers to the property of the plasma membrane to allow certain substances to pass through while restricting others. This enables the cell to maintain an internal environment conducive to its function. The plasma membrane achieves selective permeability through various mechanisms such as protein channels and transporters.
Selective Permeability
Selective Permeability
Resting membrane Potential
Cholesterol is not harmful to the plasma membrane; in fact, it plays a crucial role in maintaining the fluidity and stability of the membrane. Cholesterol helps regulate the permeability of the membrane and enhances its mechanical strength.
Yes, the cell membrane is permeable to glycerol. Glycerol is a small and uncharged molecule that can pass freely through the lipid bilayer of the cell membrane.
Selective permeability is the property that describes the plasma membrane's ability to regulate the movement of molecules into and out of the cell, allowing only certain substances to pass through while restricting others. This selective permeability is achieved through the presence of various proteins and lipid components in the membrane.
yes, cell membranes are semipermeable.
The difference in concentration of K+ and Na+ across the plasma membrane, along with the membrane's permeability to these ions, generates the resting membrane potential. This potential is essential for maintaining electrical excitability in cells, such as neurons and muscle cells, and is involved in processes like nerve signaling and muscle contraction.
Cholesterol is the plasma membrane lipid that improves rigidity and reduces permeability to water due to its ability to pack tightly between the phospholipid molecules, increasing membrane stability.