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Electroporation is a dynamic phenomenon that depends on the local transmembrane voltage at each point on the cell membrane. It is generally accepted that for a given pulse duration and shape, a specific transmembrane voltage threshold exists for the manifestation of the electroporation phenomenon (from 0.5 V to 1 V). This leads to the definition of an electric field magnitude threshold for electroporation (Eth). That is, only the cells within areas where E≧Eth are electroporated. If a second threshold (Eir) is reached or surpassed, electroporation will compromise the viability of the cells, i.e., irreversible electroporation.[2]

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Electroporation involves the application of an electric field to create temporary pores in the cell membrane, allowing molecules to enter the cell that would normally be too large or hydrophilic to pass through. The electric field disrupts the lipid bilayer, leading to the formation of aqueous pores which facilitate the movement of molecules across the membrane. This technique is commonly used in molecular Biology and biotechnology to introduce substances like DNA or drugs into cells.

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Q: How electroporation increase permeability of plasma membrane?
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What is electroporation?

Electroporation, or electropermeabilization, is a significant increase in the electrical conductivity and permeability of the cell plasma membrane caused by an externally applied electrical field. It is usually used in molecular biology as a way of introducing some substance into a cell, such as loading it with a molecular probe, a drug that can change the cell's function, or a piece of coding DNA.For more details see the link on the left


How does the permeability of the plasma membrane relate to homeostasis?

who the knows


Selective permeability refers to the fact that the plasma membrane keeps all molecules out of the cell?

Selective permeability refers to the property of the plasma membrane to allow certain substances to pass through while restricting others. This enables the cell to maintain an internal environment conducive to its function. The plasma membrane achieves selective permeability through various mechanisms such as protein channels and transporters.


What feature of the plasma membrane that keeps some substances out?

Selective Permeability


What is the feature of plasma membrane that keep some substances out?

Selective Permeability


What does the difference in the K and Na concentration on either side of the plasma membrane (and permeability of the membrane to those ions) generate?

Resting membrane Potential


Is cholesterol harmful to the plasma membrane?

Cholesterol is not harmful to the plasma membrane; in fact, it plays a crucial role in maintaining the fluidity and stability of the membrane. Cholesterol helps regulate the permeability of the membrane and enhances its mechanical strength.


What property describes the plasma membrane's ability to regulate movement of molecules into and out of the cell?

Selective permeability is the property that describes the plasma membrane's ability to regulate the movement of molecules into and out of the cell, allowing only certain substances to pass through while restricting others. This selective permeability is achieved through the presence of various proteins and lipid components in the membrane.


Is membrane permeability a major function of the plasma protein in the blood?

yes, cell membranes are semipermeable.


What is the Plasma membrane lipid that improves the rigidity of the plasma membrane and increases the membrane's impermeability to water?

Cholesterol is the plasma membrane lipid that improves rigidity and reduces permeability to water due to its ability to pack tightly between the phospholipid molecules, increasing membrane stability.


What are the important of lipids?

permeability to the plasma membrane, maintaining the fluidity , get signaling through the glycolipid as such some more...


What is the plasma membrane function that keeps materials outside the cell from going inside?

The characteristic that a plasma membrane bears is the semi-permeability. This is what keeps certain materials in while keeping certain materials out.