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Step 1: Conversion of the soluble plasma protein fibrinogen

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Step 2: Fibrin threads stick to exposed surfaces of damaged blood vessels.

Step 3: Serum, a plasma minus the clotting factors is present.

Step 4: Once formed, more clotting is supported.

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Injury causes damaged tissue cells to produce prothromin activator.

This activator, along with a clotting factor produced by the sticky platelets at the damaged site, cause prothrombin along with calcium to make thrombin.

At the same time fibrinogen is stimulated to make fibrin. The fibrin ensnares RBCs to form the clot with the platelets at the injury site.

All factors have to be there for the clotting to occur. Lack of any of them causes bleeding disorders.

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10y ago
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Q: How does the body form clots?
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