Smooth ER of hepatocytes (liver cells) is the site of the cytochrome p450 family of proteins. The CYP450 containing systems are responsible for phase I drug metabolism. Phase I drug metabolism is quite complex and is usually covered in university pharmacology courses. However simply put it can lead to the activation or deactivation of hydrophobic drugs and toxins.
The organelle you are referring to is the smooth endoplasmic reticulum (SER). It plays a key role in detoxifying harmful substances like drugs and alcohol through enzymes, as well as in synthesizing lipids and proteins. The smooth ER lacks ribosomes on its surface, unlike the rough endoplasmic reticulum, which is involved in protein synthesis.
The endoplasmic reticulum (ER) is a cell organelle that is involved in protein and lipid synthesis. There are two types of ER – rough ER, which is studded with ribosomes and involved in protein synthesis, and smooth ER, which is responsible for lipid metabolism and detoxification of drugs.
The smooth endoplasmic reticulum is the organelle responsible for producing steroid hormones through lipid metabolism and detoxifying drugs by modifying them to more water-soluble forms that can be easily excreted from the cell.
The two types of ER are rough ER (endoplasmic reticulum) and smooth ER. Rough ER has ribosomes attached to its surface, where protein synthesis occurs. Smooth ER is involved in lipid metabolism, detoxification of drugs, and storage of calcium ions.
The smooth endoplasmic reticulum (smooth ER) synthesizes lipids, including phospholipids and cholesterol. It also is involved in detoxification processes by metabolizing drugs and other toxins in the liver. Additionally, the smooth ER stores calcium ions that are important for muscle contraction.
Smooth er
Smooth ER produces steroids and lipids. Smooth ER does not require ribosomes. The enzymes help break down drugs and toxins.
Smooth ER
Synthetics do not appear in the results of a drugs test.
Smooth ER it detoxifies poisons, alcohol, and drugs
This should answer your question: Enzymes of the smooth ER help detoxify drugs and poisons, especially in liver cells. Detoxification usually involves adding hydroxyl groups to drugs, making them more soluble and easier to flush from the body. The sedative phenobarbital and other barbiturates are examples of drugs metabolized in the manner by smooth ER in liver cells. In fact, barbiturates, alcohol, and many other drugs induce the proliferation of the smooth ER and its associated detoxification enzymes. This, in turn, increases tolerance to the drugs, meaning that higher doses are required to achieve a particular affect, such as sedation. Also, because some other the detoxification enzymes have relatively broad action, the proliferation of the smooth ER in response to one drug can increase tolerance to other drugs as well. Barbiturate abuse, for example, may decrease the effectiveness of certain antibiotics and other useful drugs.
The organelle you are referring to is the smooth endoplasmic reticulum (SER). It plays a key role in detoxifying harmful substances like drugs and alcohol through enzymes, as well as in synthesizing lipids and proteins. The smooth ER lacks ribosomes on its surface, unlike the rough endoplasmic reticulum, which is involved in protein synthesis.
The endoplasmic reticulum (ER) is a cell organelle that is involved in protein and lipid synthesis. There are two types of ER – rough ER, which is studded with ribosomes and involved in protein synthesis, and smooth ER, which is responsible for lipid metabolism and detoxification of drugs.
Smooth ER makes lipids and breaks down drugs and alcohol. hope this helps. :-)
The smooth endoplasmic reticulum is the organelle responsible for producing steroid hormones through lipid metabolism and detoxifying drugs by modifying them to more water-soluble forms that can be easily excreted from the cell.
The endoplasmic reticulum (ER) is the cellular organelle responsible for synthesizing cholesterol and aiding in detoxifying poisons through processes like oxidation and conjugation. The smooth ER, a subtype of the ER, is particularly important for these functions due to its lack of ribosomes and focus on lipid metabolism and detoxification.
Smooth ER lacks ribosomes, which are protein-producing organelles. Instead, they detoxify harmful substances and turn them into harmless substances, and they are involved in the production of hormones and lipids.