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German pathologist Friedrich Daniel von Recklinghausen is credited with first describing neurofibromatosis type 1 in 1882. NF1 is often called â??von Recklinghausen syndromeâ?? as a result. Scottish JH Wishart is credited with first describing neurofibromatosis type 2 in 1820.
Neurofibromatosis is a genetic disorder, so it is not spread from person to person like a virus or bacteria. It is usually inherited from a parent who carries a mutated gene associated with the disorder. In some cases, it can also occur spontaneously due to a new mutation in an individual.
The term "spread" generally suggests a disease - which the neurofibromatoses are not. My comments refer primarily to neurofibromatosis type 1 (NF1), which I am more familiar with, but the basic genetic concepts are similar in the rarer NF2.
NF1 is a genetic anomaly, the result of a error in the fundamental code of a specific part of a specific gene. This error may be brought into the picture by a similar defect in the genes of one of the parents, or through a new error introduced in the making of the egg or sperm. About 50% cases of NF1 are inherited, and the other half are new mutations.
There are currently no indicators that NF1 is increasing or decreasing in the population - generally presumed to be about one in 3,500.
You cannot "catch" a genetic mutation such as NF, nor can it be cured. However, the many possible manifestations of NF1 can be alleviated my modern medicine, and it is possible that it will one day be controllable to the point that most people with it can live near-normal, comfortable lives.
Neurofibromatosis is an autosomal dominant disorder which means it is indeed hereditary. If a parent has neurofibromatosis (also known as NF) there is a 50% chance that each child will inherit the disorder. NF does not skip generations, so if one inherits the gene one inherits the disorder. If a child does not inherit it from a parent, then they cannot pass it along. However, it is important to note that because the NF gene is so large, with over 1000 different mutations, approximately half the cases are what are known as spontaneous mutations which means there is no family history of the disorder. However, once someone does have a spontaneous mutation of neurofibromatosis, then there is a 50 /50 chance of passing it down to any of their children.
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What is the genotype for a person with the genetic disorder Neurofibromatosis?
The genotype for Neurofibromatosis is typically inherited in an autosomal dominant pattern, caused by mutations in the NF1 gene located on chromosome 17. Individuals with Neurofibromatosis usually have a mutation in one copy of the NF1 gene.
Are there any support groups for neurofibromatosis?
Yes, there are support groups for neurofibromatosis. The Children's Tumor Foundation, NF Network, and NF Australia are some organizations that offer support and resources for individuals and families affected by neurofibromatosis. These groups provide opportunities for connections, information sharing, and emotional support.
When was neurofibromatosis discovered?
Neurofibromatosis was first described in medical literature in the late 1800s by Friedrich Daniel von Recklinghausen, a German pathologist. He characterized the condition and it was later named after him as Von Recklinghausen's disease or neurofibromatosis type 1 (NF1).
What is the difference between neurofibromatosis 1 and neurofibromatosis 2?
Neurofibromatosis 1 (NF1) is characterized by the presence of multiple neurofibromas, cafe-au-lait spots, and Lisch nodules in the eyes, while Neurofibromatosis 2 (NF2) is characterized by bilateral vestibular schwannomas leading to hearing loss, balance issues, and facial weakness. NF1 is more common and typically less severe than NF2.
What is the meaning of neurofibermatosis?
Neurofibromatosis is an autosomal dominant disorder, which means only one copy of the affected gene is needed for the disorder to develop.
How can neurofibromatosis be diagnosed?
Neurofibromatosis is usually diagnosed when the patient has 10 or more cafe-au-lait spots.
What chromosome does Neurofibromatosis effects?
WOW!! That guy is amazing. A chicken? Histerical, Neurofibromatosis affects only chromosome number 23. It also will affect the brain and is an autosomal dominant genetic disorder.It is when your chromosome has a chicken.
What is the genotype for a person with the genetic disorder Neurofibromatosis?
The genotype for Neurofibromatosis is typically inherited in an autosomal dominant pattern, caused by mutations in the NF1 gene located on chromosome 17. Individuals with Neurofibromatosis usually have a mutation in one copy of the NF1 gene.
Are there any support groups for neurofibromatosis?
Yes, there are support groups for neurofibromatosis. The Children's Tumor Foundation, NF Network, and NF Australia are some organizations that offer support and resources for individuals and families affected by neurofibromatosis. These groups provide opportunities for connections, information sharing, and emotional support.
Who does neurofibromatosis affect?
Every one idiot
Is neurofibromatosis tranferable threw intercourse?
Neurofibromatosis - is a genetic condition... nota communicable disease. You cannot 'catch' it from a sufferer by way of intercourse with an affected person.
Where can a person go to find detailed information on neurofibromatosis?
The NHS website has detailed information on neurofibromatosis. They have details of the diagnosis, causes, symptoms and possible treatments for the condition.
When was neurofibromatosis discovered?
Neurofibromatosis was first described in medical literature in the late 1800s by Friedrich Daniel von Recklinghausen, a German pathologist. He characterized the condition and it was later named after him as Von Recklinghausen's disease or neurofibromatosis type 1 (NF1).
Is there a cure for neurofibromatosis?
no, not yet, but they are working to find one!
Is neurofibromatosis occrs in India?
yes !! I suffer from NF1
What is everyday life like for a person with neurofibromatosis?
hard
Who discovered neurofibromatosis type 1?
Von Recklinghausen
