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Chargaff’s rules provided Watson and Crick with crucial information about the base pairing in DNA: adenine pairs with thymine and guanine pairs with cytosine in equal amounts. This information helped them to propose the double helix structure of DNA, with complementary base pairing along the strands.
Watson and Crick's model of the DNA molecule showed that the double helix structure allowed for complementary base pairing between adenine and thymine, and between guanine and cytosine. This explained how DNA strands could replicate and pass on genetic information accurately.
well the dna molecule model was compared to Franklins
Watson and Crick determined the three-dimensional shape of DNA through model-building and analysis of X-ray diffraction images captured by Rosalind Franklin. Their model of the double helix structure of DNA was based on the complementary base pairing of adenine-thymine and guanine-cytosine, as well as the sugar-phosphate backbone.
Uracil in Watson-Crick base-pairing though non-standard pairs exist.