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This occurs due to nondisjunction, in which one or more homologous pairs of chromosomes do not separate during anaphase I, or sister chromatids do not separate properly during anaphase II of meiosis. The resulting daughter cells (gametes) will have either 22 or 24 chromosomes. If the gamete with 22 chromosomes unites with a normal gamete with 23 chromosomes, the offspring will have 45 chromosomes (23 + 22). If the gamete with 24 chromosomes unites with a normal gamete, the offspring will have 47 chromosomes (23 + 24). These are usually lethal conditions.

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12y ago
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12y ago

If one of the parent's homologous chromosomes did not separate, and therefore their gamete contained 24 chromosomes instead of the normal 23 - this would produce an offspring with 47 chromosomes.

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11y ago

This can happen through nondisjunction. During Meiosis the chromosomes do not split apart properly, and the end result is a gamete with too many chromosomes. If a human has a gamete with two many chromosomes then it is possible that it will have 47 chromosomes instead of the normal 46. A human with 47 chromosomes has a gamete with 2N+1 instead of the normal 2N.

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9y ago

A human can get more than 46 chromosomes by an accident in the egg or sperm. When this happens it is present in every cell of the body. Some of these abnormalities can be inherited.

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14y ago

Humans have 46 total chromosomes

They have 23 pairs of homologous chromosomes. 22 pairs are autosomal chromosomes and 1 pair is sex-linked.

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11y ago

Answer: Each parent gives 23 chromosome and makes 46 chromosomes, if the baby doesn't have 46 chromosomes it may end up deaf or blind, etc.

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12y ago

Monosomy

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Q: How can a human with 47 chromosomes be produced?
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