In some tanning processes, yes. But not in others.
One very old process for tanning leather used layers of leather and animal dung, it was allowed to ferment for months. That used bacteria and fungi, but nobody knew it when the process was developed.
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Bacteria is used in the pre-tanning processes ,i.e, soaking, dehairing, bating and degreasing. And most important it produces proteolytic enzymes known as proteases which are extracted and used in dehairing, soaking and bating processes which is required to produce leather.
Leather tanning is a chemical change, as it involves the chemical reaction of tanning agents with proteins in the hide to create a more stable material. This process transforms the hide into leather by altering its chemical structure.
Oak tree bark is commonly used for tanning leather due to its high tannin content. The tannins in the bark help soften and preserve the leather, making it more durable. Oak bark tanning is a traditional method that produces a high-quality and long-lasting leather.
Natural resources used to make a pair of shoes include leather from animals, rubber from rubber trees, cotton for some components, and various metals and minerals for elements like eyelets and buckles. These resources go through processes such as tanning, rubber harvesting, and mining to be transformed into shoe components.
There isn't a specific formula for leather as it is a complex material made up of primarily collagen proteins. However, the general chemical composition of leather includes proteins, lipids, water, and some trace minerals.