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What does the medical abbreviation MHC mean?
MHC = major histocompatibility complex What makes up MHC are HLA's (human leukocyte antigens), which there are subclasses for.
When was MHC Krylya Sovetov created?
MHC Krylya Sovetov was created in 2008.
What is MHC?
Major Histocompatibility Complex
Why is it an Advantage to the population of species to have a highly polymorphic MHC region?
The advantage of having a highly polymorphic MHC is that it adds to variety of which it can bind to a peptide. If MHC cannot bind to a viral or bacterial peptide then your body cannot use its' adaptive immunity to fight off an infection. The T cell requires MHC to activate and if MHC is not binding to anything because it has such a small repertoire of alleles to create a MHC molecule, it will render T cells useless. So to have a highly polymorphic MHC gene that can encode to bind to many different peptides is advantageous for survival.
B-lymphocytes express both MHC-1 and MHC-2?
Yes they do. MHC 1 are expressed by all nucleated calls (except neurones) and platelets. MHC 11 are expressed by B-cells, macrophages and dendtitic cells. Therefore, some cells express both types.
Is MHC class 1 the same as HLA class 1?
The answer previously here about MHC referring to mice and HLA referring to humans is catagorically untrue! HLA and MHC are in fact the same, so HLA class 1 = MHC class 1. Same goes for class 2.
MHC antigens are?
Peptides
When MHC will be expressed?
Major histocompatibility complex (MHC) molecules are expressed on the surface of most nucleated cells in the body. They are involved in presenting antigens to T cells for immune recognition. MHC expression is a crucial part of the immune response to infections and diseases.
Where can one find information about the MHC?
MHC is an acronym for "major histocompatibility complex." If one desires to find out more about the MHC genetic issue, one might find reliable information on the government NIH website.
Where are major histocompatibility complex-you MHC-you molecules located?
Each individual has a unique MHC profile Clinically important MHC are HLA(human leukocyte antigens) -A, -B -DR -expression of a particular combination of MHC genes Class I - are located on all nucleated cells Class II - are located on macrophages, dendritic cells, B cells.
Difference between MHC class1 and MHC class2 molecules?
MHC class I molecules present intracellular peptides to CD8+ T cells, while MHC class II molecules present extracellular peptides to CD4+ T cells. Class I molecules are found on all nucleated cells, whereas class II molecules are primarily on antigen-presenting cells. Both classes play crucial roles in the immune response by presenting antigens to T cells.
Class II MHC molecules are found only on which of the following?
Presented by APCs as MHC-exogenous peptide complex
