Its a dog...or a cat...your choice
endogenous opioid peptides
The simple answer to this is believed to be through potentiation of endogenous opioid activity, though this is uncertain. SNRIs (not NSRIs) are essentially selective versions of TriCyclic Antidepressants. There is evidence that TCAs potentiate opioid analgaesia, which could be the mechinism of action.
There are certain endorphins that are released during vigorous exercise. These endorphins are called endogenous opioid peptides. These endorphins are also present in love.
Neurontin is not an opioid
Endogenous is an adjective to describe something produced or growing from within; originating internally. Example: The design is endogenous; I've been working it out in my head for a long time.
something
The production of endogenous VLDL is decreased by a diet high in Omega 3 and exercise.
Endogenous is internal, biological and somatic Exogensous is externally caused - environmental
The endogenous variables value is established by the conditions of the other variables in the structure. The exogenous variables value in independent of the conditions of the other variables in the structure. The difference between the endogenous and exogenous variables is the endogenous depends solely on the structure and the exogenous depend on outside elements.
An opioid is a naturally occurring compound that will bind to opioid receptors within your body. When an opioid receptor is blocked by an opioid a person is likely to feel less pain.
Endogenous opioids function primarily to relieve pain, they also appear to enhance the sensation of itching.