When writing to a woman you don't know, it is best to use "Ms." as a title, since it can mean either "Miss" or Mrs." If you don't know her, you don't know how she prefers to be addressed or whether she is married or single. (Actually, the intention of "Ms." is simply to indicate a woman, regardless of marital status.) The use of "Miss" seems rather old-fashioned in U.S. culture, so "Ms." is likely to be more acceptable and preferable.
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