Oh, dude, technically you can physically insert a marker into your butt if you really want to, but I wouldn't recommend it. Like, it's definitely not a good idea and could cause some serious harm. So, maybe just stick to using markers for drawing and leave the butt stuff out of it, okay?
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Well, mechanically it is 'possible' to do, but can be painful, is unsafe to do, can become stuck, can tear or rip delicate tissues, can make you bleed, etc. AND if it gets stuck or the top comes off, you will need to go to the emergency room. Now, you may not be aware of this, but doctors and nurses DO laugh at patients who have done medically-stupid acts. Putting any object in the rectum is a medically-stupid act. So if you want to be embarrassed, humiliated, and know you're being laughed at, then perhaps it won't bother you. However, any rectal injuries you cause to yourself will leave you in pain, crying, possibly needing to have rectal surgery, and possibly leaking feces the rest of your life. It is just not safe--don't do it.