It comes out of ancient societies trying to explain unusual deaths. They join vampires, mermaids, and fairies in explaining nature and how it works. When man doesn't know science he makes up things, creatures, and gods to explain the world he lives in.
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The myth or something similar to it has arisen independently from several different cultures around the world. Compare the Greek werewolf with the Navaho SkinWalkers, with the Windigo of the Ojibway.
Werewolves are mythological creatures, they come from stories and Fairy Tales, from someone's imagination.