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A large dog that has not been socialized with humans properly (or not at all) and/or has been treated inhumanely (by being teased, beaten, etc.) throughout its life. Strong breeds like pitbulls often get most of the blame for being the most dangerous and killer-type dogs in the world, when, in reality, it's the human behind that dog that is to blame.
All dogs are equipped with the tools necessary to kill a human. From the smallest toy breed to the largest. Some have even been bred for the art of killing. What makes it more likely that any dog will take a human life is as stated above, how the dog has been treated by humans.
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