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You can. But only in extreme conditions. I met a woman at a horse show that had spayed her mare. She had very strong heat cycles and suffered from horse PMS, for lack of a better word. It made showing very difficult. She first tried hormone treatment but that didn't work and she made the decision to have her spayed. It's a huge decision and all options should be exhausted before even thinking about spaying.

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13y ago
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Q: Can you spay a mare horse?
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